Prokaryotic promoters are the regulatory sequences that initiates the transcription of prokaryotic genes. They are, -10 promoters or element (that is present 10bp upstream of transcription start site), -35 promoters or element (that is present 35bp upstream of transcription start site).Įukaryotic promoters are the regulatory sequences that initiate the transcription of eukaryotic organisms. These sequences are classified according to their location. Out of the three promoter elements of prokaryotes, there are two main important two short DNA sequences. The less involvement of promoter elements in prokaryotes is the main reason why their transcription process is less sophisticated when compared with eukaryotic transcription that involves a higher number of promoter sequences. The prokaryotic promoter contains only three types of promoter elements. Both RNA polymerase and the sigma factor collectively identify the correct promoter region and form the transcription complex. This is a unique characteristic that is present in the prokaryotic transcription process. Therefore, it is said that each single sigma factor would recognize a single core promoter sequence. Sigma factors are unique to different promoter sequences. In prokaryotic organisms, the promoter that involves in transcription is identified by the associated factor called sigma factor. These eukaryotic promoters have the ability to span through a wide range of DNA sequences. This also explains the fact that, the effect of many regulatory sequences take place even though they are located many kilobases away from the site of transcription. It has been found out that, due to this complexity of the eukaryotic promoters, the DNA has the capability to fold back on itself. In the context of eukaryotes, there are many numbers of promoter elements are found that are highly sophisticated and more diverse than promoters. Three main portions core promoter, proximal promoter and distal promoter, collectively form a promoter. Side by Side Comparison – Eukaryotic vs Prokaryotic Promoters in Tabular FormĦ. Similarities Between Eukaryotic and Prokaryotic Promotersĥ. This is the key difference between eukaryotic and prokaryotic promoters. In eukaryotes, there are many different promoter elements such as TATA box, initiator elements, GC box, CAAT box, etc. In prokaryotes, only three types of promoter sequences are found namely, -10 promoter s, -35 promoter and upstream elements. Eukaryotic and prokaryotic promoters are different from each other. Promoters are different according to the type organism. The length of a promoter varies from 100 bp to 1000 bp. These promoters are typically found adjacent to the transcription start site. That region is known as the promoter region.

A specific region of DNA located at the 5’ end of the transcriptional unit initiates this process. Transcription is the process of converting the genetic information stored in the coding DNA sequence into mRNA sequence.

Key Difference – Eukaryotic vs Prokaryotic Promoters

Gc pro box not 5